Neurosecretory habituation in PC12 cells: modulation during parallel habituation.
نویسندگان
چکیده
منابع مشابه
Habituation of neurosecretory responses to extracellular ATP in PC12 cells.
Neuronally differentiated PC12 cells have been used as a model for habituation. These cells secrete norepinephrine in response to extracellular ATP, as well as other stimulants, and the response is diminished with repetitive stimulation. This loss of neurosecretory responsiveness displays characteristics commonly associated with habituative learning. These include an increase in both the rate a...
متن کاملThe biochemistry of the neuron. Neurosecretory habituation to repetitive depolarizations in PC12 cells.
Habituation in response to repetitive depolarization of PC12 cells can be used as a model for memory processes at the molecular level. In response to depolarization by high external potassium, a triphasic elevation in internal calcium levels occurred. Calcium elevation was maximal immediately after addition of the stimulus (phase 1), followed by a 2-min period in which the calcium level decreas...
متن کاملTherapeutic Process During Exposure: Habituation Model
The current paper outlines the habituation model of exposure process, which is a behavioral model emphasizing use of individually tailored functional analysis during exposures. This is a model of therapeutic process rather than one meant to explain the mechanism of change underlying exposure-based treatments. Habitation, or a natural decrease in anxiety level in the absence of anxiety-reducing ...
متن کاملHabituation to Galvanic Vestibular Stimulation during Gait
Balance requires the integration of proprioceptive, visual, and vestibular sensory inputs. Contributions from the vestibular system are increasingly important when other sensory signals are lacking or erroneous [1]. Galvanic vestibular stimulation (GVS), the application of a small electrical current across the mastoid processes, has been used to apply a stimulus to the vestibular system indepen...
متن کاملHabituation of attentional networks during emotion processing.
Dysfunctional emotion processing is a key aspect of many neuropsychiatric disorders. This dysfunction may be due to an abnormal magnitude of neural substrate activation during emotion processing or due to an altered time course of the neural substrate response. To better understand the temporal characteristics of the neural substrate activation underlying implicit emotion processing, nine healt...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1995
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.92.11.5052